The Faculty of Science at Cairo University is the oldest and most prestigious faculty of science in Egypt and one of the foremost in the entire Middle East and Africa. Established in 1925 as part of the Egyptian University (later renamed King Fuad I University, then Cairo University in 1954), it has been a cornerstone of scientific education and research in the Arab world for nearly a century.

The faculty was originally founded with four core departments — Mathematics, Physics, Chemistry, and Biology — mirroring the great European science faculties of the time. Today it has grown to encompass 12 specialized scientific departments covering every major discipline of the natural and applied sciences, from Astronomy and Meteorology to Biophysics and Biotechnology.

With over 300 faculty members, including more than 120 full professors, the Faculty of Science is home to some of Egypt's most distinguished scientists and researchers. Many of its alumni have gone on to become ministers, university presidents, Nobel Prize nominees, and internationally recognized scholars. The faculty has produced over 80,000 graduates since its founding.

The campus spans a significant portion of the historic Cairo University grounds in Giza, overlooking the Nile and the Great Pyramids. Its facilities include more than 150 teaching and research laboratories, a central scientific library housing over 100,000 volumes and periodicals, a natural history museum, a botanical garden, and several specialized research centers.

The Faculty of Science grants Bachelor of Science (B.Sc.) degrees, as well as postgraduate Diplomas, Master of Science (M.Sc.), and Doctor of Philosophy (Ph.D.) degrees. Its programs are accredited by the National Authority for Quality Assurance and Accreditation of Education (NAQAAE), and the faculty maintains active partnerships with leading universities across Europe, Asia, and North America.